This assignment is based on the learning objectives and concepts as  described in the Unit Learning Guide. There are 9 questions worth a  total of 64 marks and this assignment will contribute 64% towards the  total assessment for this subject.

Introduction to Clinical Epidemiology (401173)
FINAL ASSIGNMENT
Autumn, 2019
Due date: 11.59pm , May 29 2019
This assignment is based on the learning objectives and concepts as  described in the Unit Learning Guide. There are 9 questions worth a  total of 64 marks and this assignment will contribute 64% towards the  total assessment for this subject.
Your assignment should be typed, with adequate space left between  questions. Assignments should be submitted via vUWS. Be as concise as  possible in your answers, and use the number of marks allocated to each  question as a guide for how much to write.
Please note this is an individual exercise.
Late assignments will not be accepted without prior approval.
You are required to answer ALL questions (1-9)
Page 1 of 7
Answer questions 1-2 based on the following scenarios:
Q1: Fred, a 65-year-old obese man with a history of type 2 diabetes  mellitus and hypertension presents to the GP practice for a follow-up  appointment. During the consultation, he asks whether there is a better  medication to glicazide and metformin, his oral hypoglycemic  medications, which he has been taking to control his blood sugar. His  friend has recently been put on a newer oral hypoglycemic medication  (Liraglutide, a glucagon-like peptide-1 analogue), which has been shown  to help with weight management in patients with diabetes and obesity.  Fred has been finding it very difficult to lose weight for a few years  now as he has tried various lifestyle modifications. He asks whether the  new oral hypoglycemic medications could be an option for him in weight  reduction.
Task [2 marks]
a. Write a focused research question for this particular problem that  will help you organise a search of the literature for an answer (use the  PICO elements as appropriate).
b. Identify the PICO elements in your research question